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The scheme is going ahead despite the decision to wind up the six year old Central Salford Urban Regeneration Company, which had driven it.
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"The Greengate redevelopment has been the culmination of years of work with Central Salford Urban Nike Air Force 1 Low Black Suede White
Felicity Goodey, chairman of the Central Salford Urban Regeneration Company, said: "To be in a position to announce that construction is starting on site at Greengate is a great achievement for the URC and Salford city council.
Regeneration Company and the project funders at the Home And Community Agency, Northwest Development Agency and the European Regional Development Fund."
"Even though we are now facing tough economic times, it is essential we continue to harness the momentum that has built up in Salford to ensure the city, and the people living here, continue to thrive. This development will bring more investment and further boost the local economy.
"This project is critical to the regeneration not only of the Chapel Street area of Salford but to the medieval quarter of Manchester. The partnership has worked tirelessly over the last four years to unlock this development which will begin the transformation of one of the most important parts of the regional centre.
The scheme has been designed by Leeds based architects Whitelaw Turkington and internationally renowned engineers Arup. Construction work will be carried out by Carillion, who will have the first phase, including the public space, a footbridge linking the development to Nike Air Force 90
"This is another major legacy of Central Salford URC.
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ceremony to mark the start of the 450m regeneration of a neglected part of Salford was taking place today.
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Manchester, water fountains and architectural sculptures, completed by April 2012.
Launch of work to breathe new life into scruffy Salford spot
MP Hazel Blears, council leader John Merry and other dignitaries were due to take part in the ground breaking event at Greengate.
The project will transform 31 acres of semi derelict land which includes the former Manchester Exchange Station, bounded by Chapel Street and Gravel Lane. It will include new offices, hotels, shops and apartments.
It is hoped it will mirror Manchester's nearby Exchange Square, which is close to the Selfridges and Harvey Nichols stores, and is popular with shoppers, especially in summer.
Coun Merry said: "The redevelopment of this site will really unlock its potential. Over the past 10 years, Salford has been transformed as a result of significant investment.
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